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Major Milestone: Research Points To A Halt In Alzheimer’s Disease Advancement.

Does your hand shiver when the temperature is absolutely normal? Or does it take an excruciating amount of time to see the movements in your limbs? Or do you have difficulty remembering what your last meal was? Well, these are some of the examples of Alzheimer’s Disease. A cognitive disease that does not have any cure YET! 

A recent research led by New York Medical College (NYMC) and Eastern Virginia Medical College researchers was published in Nature Communications Biology. This research found a critical link between diet, inflammation, and Alzheimer’s Disease. The research states potential loopholes to stop this disease on its track and slow down the development of this disease.

Patric Stanton, a Ph.D., professor of cell biology, anatomy, and neurology at NYMC said that inflammation fuels the generation and development of Alzheimer’s Disease. Consuming high cholesterol and fatty food can further lead to inflammation. Researchers found that preventing a certain protein from activating the genes that cause inflammation can protect your brain from the side effects of these foods. 

The study also sheds light on new perspectives and treatments that can slow down the process of Alzheimer’s and stop it from progressing at all. As the Western diet includes food with high cholesterol and fat, approximately 6 billion people are suffering from this disease. It is no surprise that we need more cures and drugs to make this disease go away for good.

Progress On Understanding Alzheimer’s Disease

Another study from the National Institutes of Health states that there is a link between diabetes, metabolic syndrome, and increased risk of cognitive dysfunction. Atherosclerosis and vascular inflammation from diabetes can trigger Alzheimer’s disease. Whereas, metabolic syndrome has a clear connection with consuming a Western diet. 

Understanding Alzheimer’s Disease

This study focused on the transcription factor STAT 4, a protein involved in signaling pathways, which plays a part in inflammation activation in our body.

With STAT 4 present in the diet, there is a high probability that the body becomes sensitive to glucose and insulin, indicating signs of diabetes. It also creates an impact on the brain and memory formation.

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Early detection of the disease and brain dysfunction can give a better understanding of this cognitive disease. It can also help with the treatments and positive outcomes for the patients. There has been research recently that focuses on brain monitoring and can detect neurodegenerative diseases. 

In the 6G enabled sustainable society event, associate professor at the University of Oulu Teemu Myllyla introduced the idea of wearable technologies and direct sensing techniques for neuro hydrodynamics. This is a great breakthrough in early diagnosis and treatment monitoring of Alzheimer’s Disease. The idea is to monitor the brain activity for any signs of neurodegenerative disease which can progress before any symptoms appear. 

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Glymphometer, an innovative technology uses light to study brain fluid dynamics and potential disorders in the brain. It is capable of signaling AD patients with healthy controls based on 5-minute monitoring. The G Index, the Glymphatic system activity Index is a measure of brain clearance activity. This index monitors the sleep schedule and daily tasks to understand if any adjustments are required to reduce the risk of developing any brain disorders.

This technology will help in maintaining optimal cognitive health for individuals from 40-70 years of age. People in this age range are more likely to develop cognitive disorders. It will also open possibilities for the use of 5G and 6G in emerging healthcare applications and streamline data collection. With this innovation, there can be a clear understanding of NDD and suggestions on lifestyle changes to reduce the risk of these diseases.

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